Present Day
Neuronal lrp4 directs the development, maturation, and cytoskeletal organization of peripheral synapses
DePew, A.T., Bruckner, J.J., O’Connor-Giles, K.M., and Mosca T.J. 2024. Neuronal LRP4 directs the development, maturation, and cytoskeletal organization of peripheral synapses. BioRxiv https://doi.org/10.1101/2023.11.03.564481 (uploaded 08 Nov 2023).
Axon arrival times and physical occupancy establish visual projection neuron integration on developing dendrites in the Drosophila optic glomeruli
McFarland B.W., Jang, H., Smolin, N. Hina, B.W., Parisi M.J., Davis, K.C., Mosca T.J., Godenschwege T.A., Nern A., Kurmangaliyev, Y.Z., von Reyn, C.R. 2024. Axon arrival times and physical occupancy establish visual projection neuron integration on developing dendrites in the Drosophila optic glomeruli. BioRxiv https://doi.org/10.1101/2202.0820.504653 (uploaded 26 Jan 2024).
SynLight: a Bicistronic strategy for simultaneous active zone and cell labeling in the Drosophila nervous system
Aimino, M.A., Humenik, J., Parisi M.J., Duhart, J.C., and Mosca T.J. 2023. SynLight: A bicistronic strategy for simultaneous active zone and cell labeling in the Drosophila nervous system. G3 (Bethesda) 13(11), jkad221 (highlighted article; available online 27 Sep 2023; in print 1 Nov 2023).
A conditional strategy for cell-type-specific labeling of endogenous excitatory synapses in Drosophila
Parisi M.J., Aimino M.A., and Mosca T.J. 2023. A conditional strategy for cell-type specific labeling of endogenous excitatory synapses in Drosophila. Cell Reports Methods 3(5), 100477 (available online 11 May 2023; in print 22 May 2023).
Synaptic development in diverse olfactory neuron classes uses distinct temporal and activity-related programs
Aimino M.A., DePew A.T., Restrepo L.J. and Mosca T.J. 2023. Synaptic development in diverse olfactory neuron classes uses distinct temporal and activity-related programs. Journal of Neuroscience 43(1), 28-55 (cover article; available online 29 November 2022; in print 4 January 2023).
Gamma-secretase promotes Drosophila postsynaptic development through the cleavage of a Wnt receptor
Restrepo L.J., DePew A.T., Moese E.R., Tymanskyj S.R., Parisi M.J., Aimino M.A., Duhart J.C., Fei H., Mosca T.J. 2022. Gamma-secretase promotes Drosophila postsynaptic development through the cleavage of a Wnt receptor. Developmental Cell 57, 1643-1660 (cover article; available online 01 June 2022; in print 11 July 2022).
Genetic regulation of central synapse formation and organization in Drosophila melanogaster
Duhart J.C. and Mosca T.J. 2022. Genetic regulation of central synapse formation and organization in Drosophila melanogaster. Genetics 221(3), iyac078 (highlighted article; available online 02 June 2022; in print 1 July 2022).
Conservation and innovation: versatile roles for lrp4 in nervous system development
DePew A.T. and Mosca T.J. 2021. Conservation and innovation: versatile roles for LRP4 in nervous system development. Journal of Developmental Biology 9, 9.
Zinc finger RNA binding protein Zn72D regulates ADAR-mediated RNA editing in neurons
Sapiro A.L., Freund E.C., Restrepo L., Qiao H.H., Bhate A., Li Q., Ni J.Q., Mosca T.J., Lin, J.B. 2020. Zinc finger RNA binding protein Zn72D regulates ADAR-mediated RNA editing in neurons. Cell Reports 13, 107654.
The Tenets of Teneurin: Conserved Mechanisms Regulate Diverse Developmental Processes in the Drosophila Nervous System
DePew A.T.*, Aimino M.A.*, Mosca T.J. 2019. The tenets of Teneurin: conserved mechanisms regulate diverse developmental processes in the Drosophila nervous system. Frontiers in Neuroscience 13:27.
Rabies screen reveals GPe control of cocaine-triggered plasticity.
Beier K.T., Kim C.K., Hoerbelt P., Hung L.W., Heifets B.D., DeLoach K.E., Mosca T.J., Neuner S., Deisseroth K., Luo L., Malenka R.C. 2017. Rabies screen reveals GPe control of cocaine-triggered plasticity. Nature 549, 345-350.
Drosophila mutants lacking octopamine exhibit impairment in aversive olfactory associative learning (Commentary on Iliadi et al. (2017))
Mosca T.J. 2017. Drosophila mutants lacking octopamine exhibit impairment in aversive olfactory associative learning (Commentary on Iliadi et al., 2017). 2017. European Journal of Neuroscience 46, 2078-2079.
Presynaptic LRP4 Promotes Synapse Number and Function of Excitatory CNS Neurons
Mosca T.J., Luginbuhl D.J., Wang I.E., Luo L. 2017. Presynaptic LRP4 promotes synapse number and function of excitatory CNS neurons. Elife 6, e27347.
2016 - 2010
The Strip-Hippo pathway regulates synaptic terminal formation by modulating actin organization at the Drosophila neuromuscular synapses
Sakuma C., Saito Y., Umehara T., Kamimura K., Maeda N., Mosca T.J., Miura M., Chihara T. 2016. The Strip-Hippo pathway regulates synaptic terminal formation by modulating actin organization at the Drosophila neuromuscular synapses. Cell Rep. 1–9.
On the Teneurin Track: A New Synaptic Organization Molecule Emerges
Mosca T.J. 2015. On the Teneurin track: a new synaptic organization molecule emerges. Front. Cell. Neurosci. 9, 1–14.
Synaptic organization of the Drosophila antennal lobe and its regulation by the Teneurins
Mosca T.J., Luo L. 2014. Synaptic organization of the Drosophila antennal lobe and its regulation by the Teneurins. Elife 3, e03726.
Plum, an immunoglobulin superfamily protein, regulates axon pruning by facilitating TGF-β signaling
Yu X.M.*, Gutman I.*, Mosca T.J.*, Iram T., Ozkan E., Garcia K.C., Luo L., Schuldiner O. 2013. Plum, an immunoglobulin superfamily protein, regulates axon pruning by facilitating TGF-β signaling. Neuron 78, 456–68 (cover article).
Trans-synaptic Teneurin signalling in neuromuscular synapse organization and target choice
Mosca T.J., Hong W., Dani V.S., Favaloro V., Luo L. 2012. Trans-synaptic Teneurin signalling in neuromuscular synapse organization and target choice. Nature 484, 237–41.
Teneurins instruct synaptic partner matching in an olfactory map.
Hong W., Mosca T.J., Luo L. 2012. Teneurins instruct synaptic partner matching in an olfactory map. Nature 484, 201–7.
2010 - 2005
Drosophila Importin-α2 is involved in synapse, axon and muscle development
Mosca T.J., Schwarz T.L. 2010b. Drosophila Importin-α2 is involved in synapse, axon and muscle development. PLoS One 5, e15223.
The nuclear import of Frizzled2-C by Importins-β11 and α2 promotes postsynaptic development
Mosca T.J., Schwarz T.L. 2010a. The nuclear import of Frizzled2-C by Importins-β11 and α2 promotes postsynaptic development. Nat. Neurosci. 13, 935–43.
Importin-beta11 regulates synaptic phosphorylated mothers against decapentaplegic, and thereby influences synaptic development and function at the Drosophila neuromuscular junction
Higashi-Kovtun M.E., Mosca T.J., Dickman D.K., Meinertzhagen I.A., Schwarz T.L. 2010. Importin-beta11 regulates synaptic phosphorylated mothers against decapentaplegic, and thereby influences synaptic development and function at the Drosophila neuromuscular junction. J. Neurosci. 30, 5253–68.
Dissection of synaptic excitability phenotypes by using a dominant-negative Shaker K+ channel subunit
Mosca T.J., Carrillo R.A., White B.H., Keshishian H. 2005. Dissection of synaptic excitability phenotypes by using a dominant-negative Shaker K+ channel subunit. Proc. Natl. Acad. Sci. U. S. A. 102, 3477–82